|
gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
|
|
gptkbp:5YearSurvivalRate
|
about 30% (metastatic)
about 70% (localized)
|
|
gptkbp:affects
|
gptkb:bone
soft tissue
|
|
gptkbp:affiliatedWith
|
gptkb:Ewing_family_of_tumors
|
|
gptkbp:causedBy
|
genetic translocation
|
|
gptkbp:commonIn
|
adolescents
children
|
|
gptkbp:diagnosedBy
|
gptkb:X-rays
gptkb:CT_scan
MRI
biopsy
|
|
gptkbp:firstDescribed
|
gptkb:James_Ewing
1921
|
|
gptkbp:formsFusionGeneWith
|
gptkb:EWSR1-FLI1
|
|
gptkbp:hasNoKnown
|
environmental cause
hereditary predisposition
|
|
gptkbp:ICD-10_code
|
C40
C41
|
|
gptkbp:incidence
|
rare
about 3 cases per million per year
|
|
gptkbp:location
|
gptkb:meat
gptkb:humerus
femur
pelvis
|
|
gptkbp:MeSH_ID
|
D013545
|
|
gptkbp:mortalityRate
|
high if metastatic
|
|
gptkbp:mostCommonTranslocation
|
gptkb:t(11;22)(q24;q12)
|
|
gptkbp:OMIM
|
612219
|
|
gptkbp:originatedIn
|
mesenchymal stem cell
neuroectodermal cell
|
|
gptkbp:prognosis
|
metastasis
stage at diagnosis
tumor size
|
|
gptkbp:rareIn
|
adults
|
|
gptkbp:relatedTo
|
gptkb:PNET_(primitive_neuroectodermal_tumor)
|
|
gptkbp:riskFactor
|
male sex
Caucasian ethnicity
age (childhood/adolescence)
|
|
gptkbp:symptom
|
fever
pain
swelling
|
|
gptkbp:treatment
|
gptkb:radiation_therapy
surgery
chemotherapy
|
|
gptkbp:bfsParent
|
gptkb:James_S._Ewing
gptkb:Oskar_Lindblom
gptkb:Ewing_sarcoma
gptkb:ERG
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ewing's sarcoma
|