|
gptkbp:instanceOf
|
Ensembl gene ID
|
|
gptkbp:alias
|
gptkb:BCC7
gptkb:LFS1
gptkb:TRP53
P53
TP53 tumor protein p53
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Li-Fraumeni_syndrome
colorectal cancer
adrenocortical carcinoma
osteosarcoma
|
|
gptkbp:chromosomeArm
|
p
|
|
gptkbp:encodes
|
gptkb:TP53
|
|
gptkbp:endPoint
|
7687550
|
|
gptkbp:Entrez_Gene_ID
|
7157
|
|
gptkbp:essentialGene
|
true
|
|
gptkbp:function
|
tumor suppressor
transcription factor
|
|
gptkbp:gene
|
gptkb:TP53
|
|
gptkbp:geneType
|
protein_coding
|
|
gptkbp:hasRatOrtholog
|
gptkb:Tp53
|
|
gptkbp:hasTranscript
|
gptkb:ENST00000269305
ENST00000413465
ENST00000420246
ENST00000445888
|
|
gptkbp:hasYeastOrtholog
|
no
|
|
gptkbp:hasZebrafishOrtholog
|
tp53
|
|
gptkbp:HGNC_ID
|
HGNC:11998
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000141485
|
|
gptkbp:isHousekeepingGene
|
false
|
|
gptkbp:isTumorSuppressorGene
|
true
|
|
gptkbp:locatedOnChromosome
|
17
17p13.1
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Trp53
|
|
gptkbp:pathway
|
apoptosis
cell cycle regulation
DNA damage response
p53 signaling pathway
|
|
gptkbp:PDB
|
gptkb:2OCJ
gptkb:3KMD
1TUP
|
|
gptkbp:product
|
gptkb:cellular_tumor_antigen_p53
|
|
gptkbp:startPoint
|
7661779
|
|
gptkbp:strand
|
minus
|
|
gptkbp:UniProtID
|
P04637
|
|
gptkbp:bfsParent
|
gptkb:SLC17A7
|
|
gptkbp:bfsLayer
|
8
|