heparin-binding EGF-like growth factor (HB-EGF)
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:HBEGF
DT receptor Diphtheria toxin receptor |
| gptkbp:binds |
gptkb:heparin
EGF receptor (EGFR) ErbB4 receptor |
| gptkbp:cleaved_to |
soluble form
|
| gptkbp:discoveredBy |
1991
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:kidney gptkb:placenta heart macrophages |
| gptkbp:function |
cell proliferation
wound healing growth factor cell migration |
| gptkbp:gene |
gptkb:HBEGF
|
| gptkbp:HGNC_ID |
4840
|
| https://www.w3.org/2000/01/rdf-schema#label |
heparin-binding EGF-like growth factor (HB-EGF)
|
| gptkbp:length |
208
|
| gptkbp:locatedIn |
gptkb:human_chromosome_5
|
| gptkbp:OMIM |
126150
|
| gptkbp:postTranslationalModification |
glycosylation
proteolytic cleavage |
| gptkbp:predecessor |
transmembrane protein
|
| gptkbp:role |
angiogenesis
cancer progression tissue repair |
| gptkbp:UniProtID |
Q99075
|
| gptkbp:bfsParent |
gptkb:EGF
|
| gptkbp:bfsLayer |
7
|