|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CL100
gptkb:HVH1
gptkb:MKP-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:component
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000120129
1843
|
|
gptkbp:enzymeClassification
|
phosphatase
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
dual specificity phosphatase 1
|
|
gptkbp:function
|
regulates cellular proliferation
dephosphorylates MAP kinases
protein tyrosine/serine/threonine phosphatase activity
regulates cellular apoptosis
regulates cellular differentiation
|
|
gptkbp:GOProcess
|
response to stress
negative regulation of MAPK cascade
|
|
gptkbp:HGNC_ID
|
HGNC:3071
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dusp1
|
|
gptkbp:inducedBy
|
stress
growth factors
oxidative stress
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
|
|
gptkbp:location
|
5q35.1
|
|
gptkbp:molecularWeight
|
39 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Dusp1
|
|
gptkbp:product
|
gptkb:Dual_specificity_protein_phosphatase_1
|
|
gptkbp:regulates
|
gptkb:MAPK/ERK_pathway
gptkb:JNK_pathway
gptkb:p38_MAPK_pathway
transcriptionally regulated
post-translationally regulated
|
|
gptkbp:symbol
|
gptkb:DUSP1
|
|
gptkbp:UniProtID
|
gptkb:Q16828
|
|
gptkbp:bfsParent
|
gptkb:DUSP1
|
|
gptkbp:bfsLayer
|
7
|