Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:JNK_pathway
|
| gptkbp:alternativeName |
gptkb:MAP3K12
gptkb:DLK |
| gptkbp:associatedWith |
neurodegenerative diseases
|
| gptkbp:domain |
protein kinase domain
leucine zipper domain |
| gptkbp:enzymeCommissionNumber |
2.7.11.25
|
| gptkbp:expressedIn |
gptkb:nervous_system
brain |
| gptkbp:function |
gptkb:MAP_kinase_kinase_kinase
serine/threonine protein kinase |
| gptkbp:gene |
gptkb:MAP3K12
gptkb:DLK |
| https://www.w3.org/2000/01/rdf-schema#label |
Dual Leucine Zipper Kinase
|
| gptkbp:inhibitedBy |
gptkb:Gadd45b
|
| gptkbp:involves |
neuronal development
neuronal apoptosis axon regeneration |
| gptkbp:locatedOnChromosome |
12q13.12
|
| gptkbp:molecularWeight |
approximately 120 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Map3k12
|
| gptkbp:PDB |
gptkb:2Y9Q
|
| gptkbp:phosphorylates |
gptkb:MAP2K4
gptkb:MAP2K7 |
| gptkbp:regulates |
neurite outgrowth
neuronal cell death |
| gptkbp:UniProtID |
Q12852
|
| gptkbp:bfsParent |
gptkb:DLK
|
| gptkbp:bfsLayer |
7
|