Statements (82)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
4
|
| gptkbp:bfsParent |
gptkb:Leonard_Lowe
|
| gptkbp:appointed_by |
oral tablet
benserazide carbidopa |
| gptkbp:approves |
gptkb:1970
|
| gptkbp:brand |
Rytary
Sinemet Stalevo |
| gptkbp:class |
gptkb:protein
|
| gptkbp:contraindication |
gptkb:healthcare_organization
gptkb:pheochromocytoma |
| gptkbp:developed_by |
gptkb:Sweden
tyrosine |
| gptkbp:discovered_by |
Carlsson et al.
|
| gptkbp:first_introduced |
dopamine
|
| https://www.w3.org/2000/01/rdf-schema#label |
L-DOPA
|
| gptkbp:ingredients |
C9 H11 N O4
|
| gptkbp:interacts_with |
iron supplements
MAO inhibitors antipsychotics |
| gptkbp:is_atype_of |
N04 B A01
|
| gptkbp:is_available_on |
extended-release formulation
immediate-release formulation |
| gptkbp:is_part_of |
dopaminergic therapy
|
| gptkbp:is_used_for |
gptkb:psychologist
gptkb:restless_legs_syndrome |
| gptkbp:is_used_in |
neurodegenerative disorders
|
| gptkbp:manager |
oral
|
| gptkbp:metabolism |
dopamine
|
| gptkbp:side_effect |
nausea
vomiting orthostatic hypotension |
| gptkbp:suitable_for |
pregnant women
patients with cardiovascular disease breastfeeding women patients with certain psychiatric disorders patients with history of seizures patients with severe liver disease patients with severe kidney disease patients with active peptic ulcer disease patients with uncontrolled hypertension patients with history of obsessive-compulsive disorder patients with history of neuropsychiatric disorders patients with history of neurodegenerative disorders patients with history of neurodevelopmental disorders patients with history of neuropsychological disorders patients with history of adjustment disorders patients with history of anxiety disorders patients with history of bipolar disorder patients with history of conversion disorders patients with history of depression patients with history of dissociative disorders patients with history of drug abuse patients with history of eating disorders patients with history of factitious disorders patients with history of gender dysphoria patients with history of impulse control disorders patients with history of melanoma patients with history of neurobiological disorders patients with history of neurocognitive disorders patients with history of neuroendocrine disorders patients with history of neurogenetic disorders patients with history of neurotoxic disorders patients with history of neurotrauma disorders patients with history of neurovascular disorders patients with history of paraphilic disorders patients with history of personality disorders patients with history of pheochromocytoma patients with history of psychosis patients with history of schizophrenia patients with history of sleep disorders patients with history of somatic symptom disorders patients with history of stress-related disorders patients with history of substance use disorder patients with history of trauma-related disorders patients with history of neurophysiological disorders patients with history of sexual dysfunction disorders patients with history of neuropharmacological disorders patients with history of neuroimmunological disorders |
| gptkbp:type_of |
59-92-7
|