|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
developmental disorders
|
|
gptkbp:discoveredIn
|
gptkb:Drosophila_melanogaster
|
|
gptkbp:domain
|
gptkb:DIX_domain
DEP domain
PDZ domain
|
|
gptkbp:encodedBy
|
gptkb:DVL1_gene
gptkb:DVL2_gene
gptkb:DVL3_gene
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
gptkb:Drosophila_melanogaster
|
|
gptkbp:function
|
signal transduction
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dishevelled protein
|
|
gptkbp:interactsWith
|
gptkb:APC_protein
gptkb:Axin
gptkb:Frizzled_receptor
GSK3-beta
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:location
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:orthologIn
|
Drosophila Dishevelled
mouse Dishevelled protein
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
planar cell polarity
beta-catenin stabilization
|
|
gptkbp:UniProtID
|
gptkb:O14640_(DVL1)
gptkb:O14641_(DVL2)
Q92997 (DVL3)
|
|
gptkbp:bfsParent
|
gptkb:Frizzled/LRP5/6_receptor_complex
|
|
gptkbp:bfsLayer
|
7
|