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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Endoribonuclease_Dicer
Helicase with RNase motif protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:DICER1_syndrome
|
|
gptkbp:biologicalProcess
|
endoribonuclease activity
|
|
gptkbp:discoveredBy
|
gptkb:Gregory_J._Hannon
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|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:domain
|
helicase domain
PAZ domain
RNase III domain
|
|
gptkbp:EC_number
|
3.1.26.3
|
|
gptkbp:enzymeClassification
|
ribonuclease
|
|
gptkbp:function
|
gptkb:RNA_interference
microRNA processing
|
|
gptkbp:gene
|
DICER1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dicer
|
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gptkbp:interactsWith
|
gptkb:PACT
gptkb:AGO2
gptkb:TRBP
|
|
gptkbp:locatedOnChromosome
|
chromosome 14q32.13 (human)
|
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gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~220 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Drosophila melanogaster Dicer-1
Drosophila melanogaster Dicer-2
|
|
gptkbp:product
|
small interfering RNA
non-coding RNA
|
|
gptkbp:regulates
|
gene expression
|
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gptkbp:substrate
|
double-stranded RNA
|
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gptkbp:UniProtID
|
Q9UPY3
|
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gptkbp:bfsParent
|
gptkb:miRNA
gptkb:RNA-induced_silencing_complex
gptkb:DICER1_gene
|
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gptkbp:bfsLayer
|
7
|