|
gptkbp:instanceOf
|
gptkb:biological_pathway
|
|
gptkbp:abbreviation
|
gptkb:RNAi
|
|
gptkbp:discoveredBy
|
gptkb:Andrew_Fire
gptkb:Craig_Mello
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:effect
|
mRNA degradation
translation inhibition
|
|
gptkbp:function
|
defense against viruses
regulation of gene expression
|
|
gptkbp:hasApplication
|
gptkb:biotechnology
crop improvement
disease research
|
|
gptkbp:involves
|
gptkb:non-coding_RNA
gptkb:Dicer_enzyme
gptkb:small_interfering_RNA
RISC complex
|
|
gptkbp:mechanismOfAction
|
gene silencing
post-transcriptional regulation
|
|
gptkbp:NobelPrizeYear
|
gptkb:2006_Nobel_Prize_in_Physiology_or_Medicine
|
|
gptkbp:occurredIn
|
animals
fungi
plants
|
|
gptkbp:relatedTo
|
gptkb:antisense_RNA
gene knockdown
transcriptional gene silencing
|
|
gptkbp:studiedIn
|
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
mammalian cells
|
|
gptkbp:usedIn
|
functional genomics
therapeutic gene silencing
|
|
gptkbp:bfsParent
|
gptkb:Andrew_Fire
|
|
gptkbp:bfsLayer
|
4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RNA interference
|