Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:abbreviation |
gptkb:RNAi
|
| gptkbp:discoveredBy |
gptkb:Andrew_Fire
gptkb:Craig_Mello |
| gptkbp:discoveredIn |
1998
|
| gptkbp:effect |
mRNA degradation
translation inhibition |
| gptkbp:function |
defense against viruses
regulation of gene expression |
| gptkbp:hasApplication |
gptkb:biotechnology
crop improvement disease research |
| https://www.w3.org/2000/01/rdf-schema#label |
RNA interference
|
| gptkbp:involves |
gptkb:Dicer_enzyme
small interfering RNA non-coding RNA RISC complex |
| gptkbp:mechanismOfAction |
gene silencing
post-transcriptional regulation |
| gptkbp:NobelPrizeYear |
gptkb:2006_Nobel_Prize_in_Physiology_or_Medicine
|
| gptkbp:occurredIn |
animals
fungi plants |
| gptkbp:relatedTo |
gptkb:antisense_RNA
gene knockdown transcriptional gene silencing |
| gptkbp:studiedIn |
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster mammalian cells |
| gptkbp:usedIn |
functional genomics
therapeutic gene silencing |
| gptkbp:bfsParent |
gptkb:Andrew_Fire
|
| gptkbp:bfsLayer |
4
|