|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
Dsh homolog 3
Dsh3
KIAA0208
|
|
gptkbp:associatedWith
|
gptkb:Robinow_syndrome,_autosomal_dominant_2
neural tube defects
|
|
gptkbp:biologicalProcess
|
protein binding
frizzled binding
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:encodes
|
Dishevelled-3
|
|
gptkbp:Entrez_Gene_ID
|
1857
ENSG00000107821
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:fullName
|
Dishevelled Segment Polarity Protein 3
|
|
gptkbp:function
|
embryonic development
signal transduction
cell proliferation regulation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:3085
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DVL3
|
|
gptkbp:interactsWith
|
gptkb:Frizzled_receptors
gptkb:GSK3B
gptkb:AXIN1
gptkb:DVL1
gptkb:DVL2
gptkb:beta-catenin
CSNK1E
CSNK2A1
DAAM1
|
|
gptkbp:length
|
716
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Robinow_syndrome
neural tube defects
|
|
gptkbp:OMIM
|
601368
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Dvl3 (Mus musculus)
|
|
gptkbp:pathway
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
ubiquitination
|
|
gptkbp:proteinFamily
|
Dishevelled family
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:UniProtID
|
O14640
|
|
gptkbp:bfsParent
|
gptkb:Dishevelled_proteins
|
|
gptkbp:bfsLayer
|
7
|