|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17
p72
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodevelopmental disorders
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:encodes
|
DEAD-box helicase 17
|
|
gptkbp:Entrez_Gene_ID
|
10521
ENSG00000100201
|
|
gptkbp:expressedIn
|
gptkb:nucleus
gptkb:cytoplasm
various tissues
|
|
gptkbp:function
|
RNA binding
ATP binding
RNA helicase activity
|
|
gptkbp:GO_term
|
gptkb:GO:0003676
GO:0005634
GO:0008380
GO:0003724
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DDX17
|
|
gptkbp:interactsWith
|
gptkb:p53
gptkb:Estrogen_receptor_alpha
gptkb:DDX5
SRA1
|
|
gptkbp:involvedIn
|
RNA splicing
ribosome biogenesis
transcription regulation
|
|
gptkbp:length
|
729 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:22q13.1
|
|
gptkbp:memberOf
|
DEAD-box protein family
|
|
gptkbp:molecularWeight
|
72 kDa
|
|
gptkbp:OMIM
|
601054
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Ddx17
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:proteinFamily
|
PF00270
|
|
gptkbp:referenceGenome
|
NM_006386
NP_006377
|
|
gptkbp:regulates
|
gene expression
alternative splicing
|
|
gptkbp:structure
|
contains DEAD motif
|
|
gptkbp:subunit
|
RNA helicase complex
|
|
gptkbp:UniProtID
|
Q92841
|
|
gptkbp:bfsParent
|
gptkb:DEAD_box_protein_family
|
|
gptkbp:bfsLayer
|
8
|