|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
p68
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
prostate cancer
hepatocellular carcinoma
|
|
gptkbp:biologicalProcess
|
RNA binding
ATP binding
ATP-dependent RNA helicase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
nucleolus
|
|
gptkbp:discoveredBy
|
Jeffrey A. Steitz
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodedBy
|
DDX5 gene
|
|
gptkbp:Entrez_Gene_ID
|
1655
ENSG00000065978
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
DEAD-box helicase 5
|
|
gptkbp:function
|
gptkb:RNA_helicase
ribosome biogenesis
transcription regulation
pre-mRNA splicing
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:2746
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DDX5
|
|
gptkbp:interactsWith
|
gptkb:p53
gptkb:DDX17
estrogen receptor alpha
|
|
gptkbp:length
|
614 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q23.3
|
|
gptkbp:motif
|
DEAD (Asp-Glu-Ala-Asp)
|
|
gptkbp:OMIM
|
601478
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
acetylation
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
transcription
alternative splicing
|
|
gptkbp:relatedTo
|
gptkb:DEAD_box_protein_family
|
|
gptkbp:structure
|
contains helicase ATP-binding domain
contains helicase C-terminal domain
|
|
gptkbp:UniProtID
|
P17844
|
|
gptkbp:bfsParent
|
gptkb:DEAD_box_protein_family
|
|
gptkbp:bfsLayer
|
8
|