|
gptkbp:instanceOf
|
cytokine
|
|
gptkbp:alsoKnownAs
|
gptkb:SDF-1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
HIV infection
autoimmune diseases
inflammatory diseases
|
|
gptkbp:discoveredBy
|
T. Nagasawa
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:encodes
|
gptkb:stromal_cell-derived_factor_1
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000107562
6387
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
heart
liver
spleen
bone marrow
lymph node
|
|
gptkbp:function
|
angiogenesis
stem cell homing
chemotaxis
|
|
gptkbp:gene
|
gptkb:CXCL12
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasIsoform
|
gptkb:CXCL12-α
gptkb:CXCL12-β
gptkb:CXCL12-γ
gptkb:CXCL12-δ
gptkb:CXCL12-ε
gptkb:CXCL12-φ
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cxcl12
|
|
gptkbp:involvedIn
|
immune response
hematopoiesis
cancer metastasis
|
|
gptkbp:length
|
89 amino acids (canonical isoform)
|
|
gptkbp:locatedOnChromosome
|
10q11.1
|
|
gptkbp:molecularWeight
|
8-10 kDa
|
|
gptkbp:OMIM
|
600835
|
|
gptkbp:orthologInMouse
|
gptkb:Cxcl12
|
|
gptkbp:pathway
|
cell migration
chemokine signaling pathway
cytokine-cytokine receptor interaction
stem cell mobilization
|
|
gptkbp:product
|
secreted protein
|
|
gptkbp:recipient
|
gptkb:CXCR4
gptkb:ACKR3
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
gptkb:P48061
|
|
gptkbp:bfsParent
|
gptkb:CXCL12_gene
gptkb:SDF-1φ
|
|
gptkbp:bfsLayer
|
8
|