SDF-1

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:CXCL12
gptkbp:alternativeSplicing produces multiple isoforms
gptkbp:binds gptkb:CXCR4
gptkb:ACKR3
gptkbp:discoveredIn 1993
gptkbp:expressedIn brain
heart
liver
bone marrow
gptkbp:family CXC chemokine family
gptkbp:function cytokine
chemoattractant
gptkbp:gene gptkb:CXCL12_gene
gptkbp:hasIsoform gptkb:SDF-1α
gptkb:SDF-1β
gptkb:SDF-1γ
gptkb:SDF-1δ
gptkb:SDF-1ε
gptkb:SDF-1φ
https://www.w3.org/2000/01/rdf-schema#label SDF-1
gptkbp:involvedIn embryonic development
immune cell trafficking
hematopoiesis
gptkbp:length 89
gptkbp:locatedOnChromosome chromosome 10q11.1
gptkbp:role HIV infection
angiogenesis
cancer metastasis
stem cell homing
gptkbp:structure contains four conserved cysteines
gptkbp:UniProtID gptkb:P48061
gptkbp:bfsParent gptkb:Claudia_Grant
gptkbp:bfsLayer 6