Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
Sirtuins
|
| gptkbp:cofactor |
NAD+
|
| gptkbp:compatibleWith |
zinc
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
histone deacetylation
|
| https://www.w3.org/2000/01/rdf-schema#label |
Class III HDAC
|
| gptkbp:includes |
gptkb:SIRT1
gptkb:SIRT2 gptkb:SIRT3 gptkb:SIRT6 gptkb:SIRT7 gptkb:SIRT4 gptkb:SIRT5 |
| gptkbp:inhibitedBy |
nicotinamide
|
| gptkbp:involvedIn |
aging
metabolism stress response |
| gptkbp:memberOf |
HDAC family
|
| gptkbp:regulates |
gene expression
|
| gptkbp:studiedIn |
cancer research
neurodegenerative diseases |
| gptkbp:bfsParent |
gptkb:Histone_deacetylase
|
| gptkbp:bfsLayer |
7
|