ChREBP

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy glucose
gptkbp:alternativeSplicing ChREBP-α
ChREBP-β
gptkbp:associatedWith gptkb:diabetes
gptkb:metabolic_syndrome
obesity
gptkbp:domain bHLH/ZIP domain
gptkbp:encodedBy MLXIPL gene
gptkbp:formsHeterodimerWith gptkb:MLX
gptkbp:fullName Carbohydrate-responsive element-binding protein
gptkbp:function transcription factor
gptkbp:gene MLXIPL
https://www.w3.org/2000/01/rdf-schema#label ChREBP
gptkbp:locale gptkb:nucleus
gptkb:cytoplasm
gptkbp:organism gptkb:human
gptkb:mouse
gptkbp:phosphorylationStatus regulates activity
gptkbp:regulates gptkb:GLUT4
gptkb:FASN
gptkb:KHK
gptkb:fatty_acid_synthase
gptkb:Rgs16
gptkb:PKLR
gptkb:ACACA
gptkb:acetyl-CoA_carboxylase
gptkb:G6PC
gptkb:pentose_phosphate_pathway
gptkb:SREBP-1c
gptkb:GLUT2
gptkb:SCD1
lipid metabolism
glucose metabolism
glycolysis
insulin sensitivity
lipogenesis
energy homeostasis
adipose tissue metabolism
liver metabolism
hepatic glucose production
triglyceride synthesis
glycolytic genes
pancreatic beta cell function
ChREBP-α
ChREBP-β
ELOVL6
L-PK
TXNIP
fructose metabolism
hepatic lipid synthesis
lipogenic genes
liver-type pyruvate kinase
gptkbp:bfsParent gptkb:AMPK_pathway
gptkbp:bfsLayer 6