|
gptkbp:instanceOf
|
gptkb:protein
amino acid transporter
|
|
gptkbp:activatedBy
|
gptkb:insulin
|
|
gptkbp:alternativeName
|
gptkb:Solute_carrier_family_2,_facilitated_glucose_transporter_member_4
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodedBy
|
gptkb:SLC2A4_gene
|
|
gptkbp:Entrez_Gene_ID
|
6517
|
|
gptkbp:expressedIn
|
heart
muscle cells
fat cells
|
|
gptkbp:family
|
gptkb:SLC2_family
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
cardiac muscle
adipose tissue
|
|
gptkbp:function
|
facilitates insulin-regulated glucose uptake
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GLUT4
|
|
gptkbp:locatedOnChromosome
|
gptkb:17p13
|
|
gptkbp:location
|
gptkb:plasma_membrane
intracellular vesicles
|
|
gptkbp:molecularWeight
|
54 kDa
|
|
gptkbp:OMIM
|
138190
|
|
gptkbp:PDB
|
4PYP
|
|
gptkbp:publicTransit
|
facilitated diffusion
|
|
gptkbp:regulates
|
downregulated in obesity
upregulated by exercise
|
|
gptkbp:relatedTo
|
gptkb:type_2_diabetes
insulin resistance
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
12 transmembrane domains
|
|
gptkbp:translocatesTo
|
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
gptkb:P14672
|
|
gptkbp:bfsParent
|
gptkb:AKT1
gptkb:P48736
gptkb:ENSG00000120948
gptkb:AMPK_pathway
gptkb:ENSG00000174775
gptkb:ENSG00000130234
|
|
gptkbp:bfsLayer
|
6
|