caspase family

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy proteolytic cleavage
gptkbp:composedOf gptkb:caspase-8
gptkb:caspase-1
gptkb:caspase-9
gptkb:caspase-3
gptkb:caspase-7
gptkb:caspase-10
caspase-6
caspase-5
caspase-12
caspase-14
caspase-2
caspase-4
gptkbp:discoveredIn 1990s
gptkbp:enzymeClassification gptkb:cysteine_protease
gptkbp:foundIn animals
gptkbp:function apoptosis
inflammation
gptkbp:GO_term GO:0004197
gptkbp:hasMember executioner caspases
inflammatory caspases
initiator caspases
https://www.w3.org/2000/01/rdf-schema#label caspase family
gptkbp:namedFor Portmanteau of cysteine and aspartic acid protease
gptkbp:regulates inhibitor of apoptosis proteins
gptkbp:relatedTo immune response
cell death
gptkbp:substrate aspartic acid residues
gptkbp:bfsParent gptkb:Caspase-9
gptkb:cysteine_protease
gptkbp:bfsLayer 7