|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:application
|
gptkb:biotechnology
diagnostics
gene editing
antiviral defense
|
|
gptkbp:associatedWith
|
gptkb:CRISPR-Cas_system
|
|
gptkbp:discoveredIn
|
2002
|
|
gptkbp:foundIn
|
prokaryotes
|
|
gptkbp:fullName
|
gptkb:CRISPR-associated_proteins
|
|
gptkbp:function
|
adaptive immunity in bacteria and archaea
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cas proteins
|
|
gptkbp:mechanismOfAction
|
DNA repair
transcriptional regulation
RNA-guided DNA cleavage
RNA-guided RNA cleavage
nuclease activity
cleavage of foreign nucleic acids
helicase activity
integration of new spacers
target recognition
|
|
gptkbp:notableMember
|
gptkb:Cas9
gptkb:Cas12
gptkb:Cas13
gptkb:Cas1
gptkb:Cas2
gptkb:Cas3
|
|
gptkbp:relatedTo
|
gptkb:CRISPR_array
gptkb:adaptation
interference
spacer acquisition
|
|
gptkbp:structure
|
varies by type
|
|
gptkbp:studiedIn
|
gptkb:biotechnology
genetics
microbiology
molecular biology
|
|
gptkbp:type
|
Type I
Type II
Type V
Type III
Type IV
Type VI
|
|
gptkbp:usedBy
|
gptkb:Bacteria
archaea
|
|
gptkbp:usedIn
|
gptkb:CRISPR-Cas12_system
gptkb:CRISPR-Cas9_system
gptkb:CRISPR-Cas1/2_system
gptkb:CRISPR-Cas13_system
gptkb:CRISPR-Cas3_system
genome editing
|
|
gptkbp:bfsParent
|
gptkb:Clustered_Regularly_Interspaced_Short_Palindromic_Repeats
|
|
gptkbp:bfsLayer
|
6
|