Statements (62)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Genetics
|
| gptkbp:advocated_for |
gptkb:scientists
policy makers bioethicists |
| gptkbp:allows |
targeted DNA modification
|
| gptkbp:collaborated_with |
universities
research institutions biotech companies |
| gptkbp:composed_of |
Cas9 protein
CRISPR RNA (cr RNA) trans-activating CRISPR RNA (tracr RNA) |
| gptkbp:developed_by |
gptkb:Emmanuelle_Charpentier
gptkb:Jennifer_Doudna |
| gptkbp:enables |
gene replacement
gene insertion gene knockout |
| gptkbp:first_introduced |
gptkb:2012
|
| gptkbp:first_published |
Science journal
|
| gptkbp:future_prospects |
enhance crop resilience
create gene drives treat genetic diseases |
| gptkbp:has_applications_in |
gptkb:biotechnology
genetic disorders cancer research agricultural enhancement |
| gptkbp:has_limitations |
regulatory challenges
delivery methods target specificity |
| https://www.w3.org/2000/01/rdf-schema#label |
CRISPR-Cas9 system
|
| gptkbp:is_applied_in |
gptkb:biotechnology
gptkb:Medicine agriculture |
| gptkbp:is_based_on |
RNA-guided DNA targeting
|
| gptkbp:is_considered |
accessible technology
revolutionary tool game changer in genetics |
| gptkbp:is_criticized_for |
designer babies
ecological impact potential misuse |
| gptkbp:is_influenced_by |
advancements in genomics
advancements in molecular biology advancements in bioengineering |
| gptkbp:is_part_of |
CRISPR technology family
genome editing toolkit |
| gptkbp:is_promoted_by |
gptkb:media
gptkb:scientific_community public interest groups |
| gptkbp:is_regulated_by |
government agencies
|
| gptkbp:is_studied_in |
model organisms
|
| gptkbp:is_subject_to |
patents
|
| gptkbp:is_supported_by |
bioinformatics tools
genome databases |
| gptkbp:is_used_by |
gptkb:researchers
agricultural scientists clinicians |
| gptkbp:is_used_in |
clinical trials
|
| gptkbp:issues |
off-target effects
ethical implications |
| gptkbp:originated_in |
bacterial immune system
|
| gptkbp:used_for |
gene editing
|
| gptkbp:bfsParent |
gptkb:Emmanuelle_Charpentier
|
| gptkbp:bfsLayer |
3
|