|
gptkbp:instanceOf
|
gptkb:chemical_compound
|
|
gptkbp:ATCCode
|
gptkb:N02BA01
|
|
gptkbp:bioavailability
|
80-100%
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:contraindication
|
Peptic ulcer
Aspirin allergy
Hemophilia
|
|
gptkbp:drugClass
|
analgesic
Antipyretic
nonsteroidal anti-inflammatory drug
Platelet aggregation inhibitor
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
Kidney
|
|
gptkbp:hasInChIKey
|
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
|
gptkbp:hasLogP
|
1.19
|
|
gptkbp:hasMolecularFormula
|
C9H8O4
|
|
gptkbp:hasSMILES
|
CC(=O)Oc1ccccc1C(=O)O
|
|
gptkbp:hasUNII
|
R16CO5Y76E
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CHEMBL29
|
|
gptkbp:indication
|
gptkb:Pain
Fever
Inflammation
Prevention of cardiovascular events
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:isOverTheCounter
|
true
|
|
gptkbp:IUPACName
|
2-acetoxybenzoic acid
|
|
gptkbp:mechanismOfAction
|
Cyclooxygenase inhibitor
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:molecularWeight
|
180.16
|
|
gptkbp:name
|
gptkb:Aspirin
|
|
gptkbp:pregnancyCategory
|
D (third trimester)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL29
2244
DB00945
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Rectal
|
|
gptkbp:sideEffect
|
Allergic reaction
Gastrointestinal bleeding
Ulcer
|
|
gptkbp:solubility
|
3.3 g/L (25°C)
|
|
gptkbp:synonym
|
gptkb:ASA
gptkb:Acetylsalicylic_acid
|
|
gptkbp:target
|
gptkb:COX-2
gptkb:PTGS2
gptkb:COX-1
gptkb:PTGS1
|
|
gptkbp:bfsParent
|
gptkb:ampicillin
|
|
gptkbp:bfsLayer
|
6
|