Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
analgesic Antiplatelet drug Antipyretic nonsteroidal anti-inflammatory drug Carboxylic acid World Health Organization essential medicine Salicylate ester |
| gptkbp:aroma |
Odorless or faint vinegar-like odor
|
| gptkbp:ATCCode |
gptkb:N02BA01
|
| gptkbp:brand |
gptkb:Aspirin
|
| gptkbp:CASNumber |
50-78-2
|
| gptkbp:chemicalFormula |
C9H8O4
|
| gptkbp:color |
White
|
| gptkbp:contraindication |
Aspirin allergy
Children with viral infections Hemophilia Active peptic ulcer |
| gptkbp:discoveredBy |
gptkb:Felix_Hoffmann
|
| gptkbp:discoveredIn |
1897
|
| gptkbp:eliminationHalfLife |
15–30 hours (high dose)
2–3 hours (low dose) |
| gptkbp:excretion |
Kidney
|
| gptkbp:flavor |
Slightly bitter
|
| https://www.w3.org/2000/01/rdf-schema#label |
Acetylsalicylic acid
|
| gptkbp:IUPACName |
2-acetyloxybenzoic acid
|
| gptkbp:KEGGID |
D00109
|
| gptkbp:legalStatus |
Over-the-counter
|
| gptkbp:mechanismOfAction |
Inhibits cyclooxygenase (COX-1 and COX-2)
|
| gptkbp:meltingPoint |
135°C
|
| gptkbp:MeSH_ID |
D001241
|
| gptkbp:metabolism |
Liver
|
| gptkbp:molecularWeight |
180.16 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
D (third trimester, US) |
| gptkbp:PubChem_CID |
2244
CHEMBL25 DB00945 |
| gptkbp:riskFactor |
gptkb:Reye's_syndrome_in_children
|
| gptkbp:routeOfAdministration |
gptkb:Oral
Rectal |
| gptkbp:sideEffect |
Allergic reaction
Gastrointestinal bleeding Stomach ulcer |
| gptkbp:solubility |
3 g/L (20°C)
|
| gptkbp:UNII |
R16CO5Y76E
|
| gptkbp:usedFor |
Fever reduction
Inflammation reduction Pain relief Prevention of blood clots |
| gptkbp:bfsParent |
gptkb:ASA
gptkb:DB00169 gptkb:Aspirin gptkb:CHEMBL960 gptkb:CHEMBL92 |
| gptkbp:bfsLayer |
6
|