|
gptkbp:instanceOf
|
gptkb:analgesic
gptkb:Antiplatelet_drug
gptkb:Antipyretic
gptkb:chemical_compound
gptkb:nonsteroidal_anti-inflammatory_drug
gptkb:World_Health_Organization_essential_medicine
gptkb:Carboxylic_acid
gptkb:Salicylate_ester
|
|
gptkbp:aroma
|
Odorless or faint vinegar-like odor
|
|
gptkbp:ATCCode
|
gptkb:N02BA01
|
|
gptkbp:brand
|
gptkb:Aspirin
|
|
gptkbp:CASNumber
|
50-78-2
|
|
gptkbp:chemicalFormula
|
C9H8O4
|
|
gptkbp:color
|
White
|
|
gptkbp:contraindication
|
Aspirin allergy
Children with viral infections
Hemophilia
Active peptic ulcer
|
|
gptkbp:discoveredBy
|
gptkb:Felix_Hoffmann
|
|
gptkbp:discoveredIn
|
1897
|
|
gptkbp:eliminationHalfLife
|
15–30 hours (high dose)
2–3 hours (low dose)
|
|
gptkbp:excretion
|
Kidney
|
|
gptkbp:flavor
|
Slightly bitter
|
|
gptkbp:IUPACName
|
2-acetyloxybenzoic acid
|
|
gptkbp:KEGGID
|
D00109
|
|
gptkbp:legalStatus
|
Over-the-counter
|
|
gptkbp:mechanismOfAction
|
Inhibits cyclooxygenase (COX-1 and COX-2)
|
|
gptkbp:meltingPoint
|
135°C
|
|
gptkbp:MeSH_ID
|
D001241
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:molecularWeight
|
180.16 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
D (third trimester, US)
|
|
gptkbp:PubChem_CID
|
2244
CHEMBL25
DB00945
|
|
gptkbp:riskFactor
|
gptkb:Reye's_syndrome_in_children
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Rectal
|
|
gptkbp:sideEffect
|
Allergic reaction
Gastrointestinal bleeding
Stomach ulcer
|
|
gptkbp:solubility
|
3 g/L (20°C)
|
|
gptkbp:UNII
|
R16CO5Y76E
|
|
gptkbp:usedFor
|
Fever reduction
Inflammation reduction
Pain relief
Prevention of blood clots
|
|
gptkbp:bfsParent
|
gptkb:ASA
gptkb:Aspirin
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Acetylsalicylic acid
|