Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
CEBP-alpha
TCF14 NFB2 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:acute_myeloid_leukemia
|
| gptkbp:clinicalTrialPhase |
available
|
| gptkbp:discoveredBy |
gptkb:Steven_L._McKnight
|
| gptkbp:encodes |
CCAAT/enhancer-binding protein alpha protein
|
| gptkbp:Entrez_Gene_ID |
1050
|
| gptkbp:expressedIn |
liver
adipose tissue hematopoietic cells |
| gptkbp:fullName |
CCAAT/enhancer-binding protein alpha
|
| gptkbp:function |
regulation of cell cycle
transcription factor regulation of myeloid differentiation |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
gptkb:CEBPA
|
| https://www.w3.org/2000/01/rdf-schema#label |
CEBPA gene
|
| gptkbp:length |
358 amino acids
2,000 base pairs (approximate) |
| gptkbp:locatedOnChromosome |
19
19q13.11 |
| gptkbp:mutationAssociatedWith |
germline
somatic familial acute myeloid leukemia |
| gptkbp:OMIM |
116897
|
| gptkbp:orthologInMouse |
Cebpa
|
| gptkbp:pathway |
hematopoiesis
adipogenesis gluconeogenesis |
| gptkbp:regulates |
gptkb:GATA1
gptkb:bZIP_family gptkb:E2F1 gptkb:BCL2 gptkb:PU.1 gptkb:p21_(CDKN1A) gptkb:cyclin-dependent_kinases cell cycle arrest adipogenesis gluconeogenesis granulocyte differentiation myeloid lineage commitment G-CSF receptor expression of adipocyte genes expression of metabolic genes expression of myeloid genes granulocyte colony-stimulating factor receptor |
| gptkbp:UniProtID |
P49715
|
| gptkbp:bfsParent |
gptkb:Liver-enriched_inhibitory_protein
|
| gptkbp:bfsLayer |
8
|