Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:p16INK4a
gptkb:cyclin-dependent_kinase_inhibitor_2A |
| gptkbp:encodedBy |
gptkb:CDKN2A_gene
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
tumor suppressor
|
| https://www.w3.org/2000/01/rdf-schema#label |
CDKN2A protein
|
| gptkbp:inhibitedBy |
gptkb:CDK4
gptkb:CDK6 |
| gptkbp:involvedIn |
cell cycle regulation
|
| gptkbp:length |
156 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_9p21
|
| gptkbp:molecularWeight |
16 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:glioblastoma
gptkb:familial_atypical_multiple_mole_melanoma_syndrome melanoma pancreatic cancer |
| gptkbp:OMIM |
600160
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:prevention |
phosphorylation of RB1 protein
|
| gptkbp:regulates |
G1 phase of cell cycle
|
| gptkbp:structure |
contains ankyrin repeats
|
| gptkbp:UniProtID |
gptkb:P42771
|
| gptkbp:bfsParent |
gptkb:p16INK4a
|
| gptkbp:bfsLayer |
7
|