|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:decay-accelerating_factor
gptkb:DAF
|
|
gptkbp:antibodyTarget
|
yes
|
|
gptkbp:associatedWith
|
cancer progression
inflammatory diseases
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Peter_Lachmann
|
|
gptkbp:discoveredIn
|
1969
|
|
gptkbp:domain
|
gptkb:complement_control_protein_(CCP)_domains
|
|
gptkbp:encodedBy
|
gptkb:CD55_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000196352
1604
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
endothelial cells
erythrocytes
epithelial cells
|
|
gptkbp:externalLink
|
https://www.ncbi.nlm.nih.gov/gene/1604
https://www.uniprot.org/uniprot/P08174
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
regulation of complement system
protection of host cells from complement-mediated lysis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:2662
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD55
|
|
gptkbp:interactsWith
|
gptkb:complement_proteins_C3b_and_C4b
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q32
|
|
gptkbp:molecularWeight
|
~70 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased susceptibility to complement-mediated lysis
|
|
gptkbp:OMIM
|
125240
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:1H03
|
|
gptkbp:postTranslationalModification
|
gptkb:GPI-anchor
|
|
gptkbp:RefSeq
|
gptkb:NM_000574
|
|
gptkbp:regulates
|
complement activation
|
|
gptkbp:relatedTo
|
autoimmune diseases
immune response
malaria infection
|
|
gptkbp:significance
|
gptkb:paroxysmal_nocturnal_hemoglobinuria
gptkb:CHAPLE_syndrome
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:UniProtID
|
gptkb:P08174
|
|
gptkbp:usedIn
|
blood group typing
|
|
gptkbp:bfsParent
|
gptkb:PNH
|
|
gptkbp:bfsLayer
|
6
|