|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:decay-accelerating_factor
|
|
gptkbp:associatedWith
|
gptkb:paroxysmal_nocturnal_hemoglobinuria
gptkb:CHAPLE_syndrome
|
|
gptkbp:biologicalProcess
|
immune response
complement binding
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Peter_Lachmann
|
|
gptkbp:encodes
|
CD55 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000196352
1604
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
endothelial cells
erythrocytes
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:function
|
regulation of complement activation
protection of host cells from complement-mediated lysis
|
|
gptkbp:HGNC_ID
|
2664
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD55 gene
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
1q32.2
|
|
gptkbp:mutationAssociatedWith
|
complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy
|
|
gptkbp:OMIM
|
125240
|
|
gptkbp:orthologInMouse
|
Cd55
|
|
gptkbp:product
|
gptkb:protein
CD55 protein
|
|
gptkbp:proteinFamily
|
complement regulatory proteins
|
|
gptkbp:UniProtID
|
gptkb:P08174
|
|
gptkbp:bfsParent
|
gptkb:CD55
|
|
gptkbp:bfsLayer
|
7
|