Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:CD55
gptkb:DAF |
| gptkbp:discoveredBy |
gptkb:Peter_Lachmann
|
| gptkbp:discoveredIn |
1969
|
| gptkbp:encodedBy |
gptkb:CD55_gene
|
| gptkbp:Entrez_Gene_ID |
1604
|
| gptkbp:expressedIn |
gptkb:leukocytes
endothelial cells erythrocytes epithelial cells |
| gptkbp:foundIn |
gptkb:cell_membrane
|
| gptkbp:function |
regulation of complement system
inhibits complement activation |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_1q32
|
| gptkbp:molecularWeight |
~70 kDa
|
| gptkbp:OMIM |
125240
|
| gptkbp:presentIn |
humans
other mammals |
| gptkbp:prevention |
complement-mediated cell lysis
formation of C3 convertase formation of C5 convertase |
| gptkbp:significance |
gptkb:paroxysmal_nocturnal_hemoglobinuria
autoimmune diseases |
| gptkbp:structure |
gptkb:protein
contains four short consensus repeats (SCRs) |
| gptkbp:UniProtID |
gptkb:P08174
|
| gptkbp:bfsParent |
gptkb:CD55
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
decay-accelerating factor
|