Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:alternativeName |
gptkb:CD55
gptkb:DAF |
gptkbp:discoveredBy |
gptkb:Peter_Lachmann
|
gptkbp:discoveredIn |
1969
|
gptkbp:encodedBy |
gptkb:CD55_gene
|
gptkbp:Entrez_Gene_ID |
1604
|
gptkbp:expressedIn |
gptkb:leukocytes
endothelial cells erythrocytes epithelial cells |
gptkbp:foundIn |
gptkb:cell_membrane
|
gptkbp:function |
regulation of complement system
inhibits complement activation |
https://www.w3.org/2000/01/rdf-schema#label |
decay-accelerating factor
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_1q32
|
gptkbp:molecularWeight |
~70 kDa
|
gptkbp:OMIM |
125240
|
gptkbp:presentIn |
humans
other mammals |
gptkbp:prevention |
complement-mediated cell lysis
formation of C3 convertase formation of C5 convertase |
gptkbp:significance |
gptkb:paroxysmal_nocturnal_hemoglobinuria
autoimmune diseases |
gptkbp:structure |
gptkb:protein
contains four short consensus repeats (SCRs) |
gptkbp:UniProtID |
gptkb:P08174
|
gptkbp:bfsParent |
gptkb:CD55
|
gptkbp:bfsLayer |
7
|