Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:insulin-like_growth_factor_1_receptor
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:formsComplexWith |
gptkb:insulin_receptor
|
| gptkbp:foundIn |
gptkb:human
|
| gptkbp:function |
mediates cell growth and survival
receptor for insulin-like growth factor 1 |
| gptkbp:gene |
gptkb:IGF1R
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD221
|
| gptkbp:involvedIn |
cellular signaling
|
| gptkbp:locatedOnChromosome |
15q26.3
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
~155 kDa
|
| gptkbp:OMIM |
147370
|
| gptkbp:phosphorylates |
tyrosine residues
|
| gptkbp:structure |
cell surface receptor
|
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:UniProtID |
gptkb:P08069
|
| gptkbp:bfsParent |
gptkb:IGF1_receptor
gptkb:IGF-1R gptkb:insulin-like_growth_factor_1_receptor |
| gptkbp:bfsLayer |
7
|