B-lymphocyte antigen CD19

URI: https://gptkb.org/entity/B-lymphocyte_antigen_CD19
GPTKB entity
Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Cluster_of_Differentiation_19
gptkb:CD19
gptkbp:compatibleWith gptkb:NK_cells
gptkb:T_cells
myeloid cells
plasma cells
gptkbp:encodedBy gptkb:CD19_gene
gptkbp:Entrez_Gene_ID gptkb:CD19
gptkbp:expressedIn mature B cells
precursor B cells
gptkbp:foundIn gptkb:B_cells
gptkbp:function B cell activation
B cell development
B cell signaling
gptkbp:HGNC_ID gptkb:HGNC:1633
https://www.w3.org/2000/01/rdf-schema#label B-lymphocyte antigen CD19
gptkbp:interactsWith gptkb:CD225
gptkb:CD21
gptkb:CD81
gptkbp:locatedOnChromosome gptkb:16p11.2
gptkbp:location gptkb:cell_membrane
gptkbp:marking gptkb:B_cells
gptkbp:molecularWeight ~95 kDa
gptkbp:mutationAssociatedWith immunodeficiency
gptkbp:OMIM 107265
gptkbp:role humoral immunity
gptkbp:significance B cell malignancies
gptkbp:target gene therapy
monoclonal antibodies
gptkbp:UniProtID gptkb:P15391
gptkbp:usedAs diagnostic marker
therapeutic target
gptkbp:usedIn immunophenotyping
gptkbp:bfsParent gptkb:CD19
gptkbp:bfsLayer 6