axicabtagene ciloleucel

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:drug
gene therapy
gptkbp:administeredAfter lymphodepleting chemotherapy
gptkbp:administeredBy specialized treatment centers
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
2017-10-18
gptkbp:ATCCode L01XL08
gptkbp:blackBoxWarning yes
gptkbp:brand gptkb:Yescarta
gptkbp:cost high
gptkbp:developer gptkb:Kite_Pharma
gptkbp:drugClass immunotherapy
https://www.w3.org/2000/01/rdf-schema#label axicabtagene ciloleucel
gptkbp:indication gptkb:primary_mediastinal_large_B-cell_lymphoma
relapsed or refractory large B-cell lymphoma
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Kite_Pharma
gptkbp:marketedAs gptkb:Gilead_Sciences
gptkbp:mechanismOfAction CD19-directed genetically modified autologous T cell immunotherapy
gptkbp:pregnancyCategory not established
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect cytokine release syndrome
neurological toxicities
gptkbp:source autologous T cells
gptkbp:storage cryopreserved
gptkbp:target gptkb:CD19
gptkbp:bfsParent gptkb:CD19
gptkb:Yescarta
gptkbp:bfsLayer 6