C-X-C motif chemokine ligand 12

URI: https://gptkb.org/entity/C-X-C_motif_chemokine_ligand_12
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf cytokine
gptkbp:alsoKnownAs gptkb:CXCL12
gptkb:stromal_cell-derived_factor_1
gptkbp:associatedWith gptkb:cancer
HIV infection
inflammatory diseases
gptkbp:binds gptkb:CXCR4
gptkb:ACKR3
gptkbp:discoveredBy gptkb:Tashiro_et_al.
gptkbp:discoveredIn 1993
gptkbp:encodedBy gptkb:CXCL12_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000107562
gptkbp:expressedIn gptkb:cancer
brain
heart
liver
bone marrow
gptkbp:function angiogenesis
hematopoiesis
chemotaxis
gptkbp:gene gptkb:CXCL12
gptkbp:HGNC_ID 10672
https://www.w3.org/2000/01/rdf-schema#label C-X-C motif chemokine ligand 12
gptkbp:involvedIn embryonic development
cancer metastasis
immune cell migration
gptkbp:locatedOnChromosome gptkb:chromosome_10
gptkbp:molecularWeight 10 kDa
gptkbp:OMIM 600835
gptkbp:orthologInMouse gptkb:Cxcl12
gptkbp:pathway chemokine signaling pathway
cell migration pathway
gptkbp:PDB 1QG7
gptkbp:product secreted protein
gptkbp:RefSeq NM_000609
gptkbp:sequence 89 amino acids
gptkbp:UniProtID gptkb:P48061
gptkbp:bfsParent gptkb:CXCL12_gene
gptkbp:bfsLayer 8