Binding immunoglobulin protein

URI: https://gptkb.org/entity/Binding_immunoglobulin_protein
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:BiP
gptkb:GRP78
gptkbp:discoveredIn 1977
gptkbp:encodedBy HSPA5 gene
gptkbp:family gptkb:heat_shock_protein_70_family
gptkbp:function protein folding
unfolded protein response
molecular chaperone
prevents aggregation of misfolded proteins
https://www.w3.org/2000/01/rdf-schema#label Binding immunoglobulin protein
gptkbp:interactsWith co-chaperones
misfolded proteins
gptkbp:involvedIn protein quality control
ER stress response
gptkbp:locatedIn gptkb:endoplasmic_reticulum
gptkbp:marking ER stress
gptkbp:molecularWeight 78 kDa
gptkbp:postTranslationalModification phosphorylation
glycosylation
gptkbp:regulates ER-associated degradation
protein translocation into ER
ER homeostasis
gptkbp:role gptkb:cancer
gptkb:virus
gptkb:diabetes
neurodegenerative diseases
gptkbp:species gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:structure ATPase domain
substrate-binding domain
gptkbp:bfsParent gptkb:Bip_(gene)
gptkb:Bip_(protein)
gptkbp:bfsLayer 6