|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:SMARCA4
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
chromatin organization
regulation of transcription
DNA binding
ATPase activity
|
|
gptkbp:component
|
gptkb:SWI/SNF_complex
|
|
gptkbp:discoveredBy
|
gptkb:Winston_and_Carlson,_1992
|
|
gptkbp:domain
|
gptkb:HSA_domain
gptkb:bromodomain
helicase domain
|
|
gptkbp:encodedBy
|
gptkb:SMARCA4_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000127616
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
chromatin remodeling
|
|
gptkbp:gene
|
gptkb:SMARCA4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BRG1
|
|
gptkbp:inhibitedBy
|
small molecule inhibitors
|
|
gptkbp:interactsWith
|
gptkb:BAF155
gptkb:BAF170
gptkb:ARID1A
gptkb:p53
|
|
gptkbp:length
|
1647 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
rhabdoid tumor
tumor suppressor loss
|
|
gptkbp:OMIM
|
603254
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
6LTJ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:RefSeq
|
gptkb:NM_003072
|
|
gptkbp:regulates
|
cell differentiation
DNA repair
cell cycle
|
|
gptkbp:requires
|
embryonic development
stem cell maintenance
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:target
|
cancer therapy research
|
|
gptkbp:UniProtID
|
gptkb:P51532
|
|
gptkbp:bfsParent
|
gptkb:SMARCA4
gptkb:SMARCB1
|
|
gptkbp:bfsLayer
|
6
|