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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:BRG1
|
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gptkbp:associatedWith
|
gptkb:cancer
gptkb:Coffin-Siris_syndrome
small cell carcinoma of the ovary, hypercalcemic type
|
|
gptkbp:biologicalProcess
|
DNA binding
ATPase activity
|
|
gptkbp:discoveredBy
|
1994
|
|
gptkbp:encodes
|
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000127616
6597
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
transcription regulation
chromatin remodeling
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:11100
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SMARCA4
|
|
gptkbp:interactsWith
|
gptkb:ARID1A
gptkb:ACTL6A
gptkb:SMARCB1
gptkb:SMARCC1
gptkb:SMARCC2
BAF complex proteins
|
|
gptkbp:length
|
1647 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:memberOf
|
gptkb:SWI/SNF_chromatin_remodeling_complex
|
|
gptkbp:mutationAssociatedWith
|
loss of function mutations can cause cancer
|
|
gptkbp:OMIM
|
603254
|
|
gptkbp:orthologInFruitFly
|
brm
|
|
gptkbp:orthologInMouse
|
Smarca4
|
|
gptkbp:orthologInYeast
|
SNF2
|
|
gptkbp:orthologInZebrafish
|
smarca4a
|
|
gptkbp:PDB
|
6LTJ
6HAY
6LTH
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:UniProtID
|
gptkb:P51532
|
|
gptkbp:bfsParent
|
gptkb:ARID1A
|
|
gptkbp:bfsLayer
|
5
|