|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:BRG1
SNF2-beta
hBRG1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Coffin-Siris_syndrome
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:encodes
|
BRG1 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000127616
6597
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
chromatin remodeling
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:1100
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SMARCA4 gene
|
|
gptkbp:interactsWith
|
gptkb:ARID1A
gptkb:ARID1B
gptkb:ACTL6A
gptkb:BAF_complex
gptkb:SMARCB1
gptkb:SMARCC1
gptkb:SMARCC2
SMARCD1
SMARCE1
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
gptkb:chromosome_19
|
|
gptkbp:memberOf
|
gptkb:SWI/SNF_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:medulloblastoma
rhabdoid tumor
tumor suppressor loss
small cell carcinoma of the ovary, hypercalcemic type
|
|
gptkbp:OMIM
|
603254
|
|
gptkbp:orthologInFly
|
brm
|
|
gptkbp:orthologInMouse
|
Smarca4
|
|
gptkbp:orthologInWorm
|
let-526
|
|
gptkbp:orthologInYeast
|
SNF2
|
|
gptkbp:product
|
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
|
|
gptkbp:proteinFamily
|
gptkb:bromodomain
ATPase domain
helicase domain
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
DNA repair
gene expression
transcription
|
|
gptkbp:UniProtID
|
gptkb:P51532
|
|
gptkbp:bfsParent
|
gptkb:BRG1
|
|
gptkbp:bfsLayer
|
7
|