BDNF (brain-derived neurotrophic factor)

URI: https://gptkb.org/entity/BDNF_(brain-derived_neurotrophic_factor)
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:neurotrophin
gptkbp:affects gptkb:basal_forebrain
gptkb:cortex
hippocampus
gptkbp:discoveredBy gptkb:Yves-Alain_Barde
gptkbp:discoveredIn 1982
gptkbp:encodedBy gptkb:BDNF_gene
gptkbp:foundIn brain
peripheral nervous system
gptkbp:function supports survival of existing neurons
involved in synaptic plasticity
encourages growth and differentiation of new neurons and synapses
gptkbp:locatedOnChromosome gptkb:chromosome_11_(human)
gptkbp:recipient gptkb:p75NTR
gptkb:TrkB
gptkbp:regulates exercise increases BDNF levels
stress decreases BDNF levels
gptkbp:relatedTo gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
gptkb:depression
gptkb:Huntington's_disease
gptkb:autism_spectrum_disorder
gptkb:long-term_potentiation
addiction
bipolar disorder
epilepsy
memory
schizophrenia
learning
obesity
neurodegenerative diseases
pain modulation
cognitive function
sleep
eating disorders
plasticity
stroke recovery
neurogenesis
anxiety disorders
axon growth
dendrite growth
mood regulation
antidepressant response
synaptogenesis
Val66Met polymorphism
gptkbp:UniProtID gptkb:P23560
gptkbp:bfsParent gptkb:CREB_(cAMP_response_element-binding_protein)
gptkb:Neurotrophin_signaling_pathway
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label BDNF (brain-derived neurotrophic factor)