long-term potentiation

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf neurophysiological phenomenon
gptkbp:abbreviation gptkb:LTP
gptkbp:category neuroscience
synaptic transmission
memory formation
gptkbp:discoveredBy gptkb:Timothy_Bliss
gptkb:Terje_Lømo
gptkbp:discoveredIn 1973
gptkbp:duration hours to days or longer
gptkbp:firstObserved rabbit hippocampus
https://www.w3.org/2000/01/rdf-schema#label long-term potentiation
gptkbp:inducedBy high-frequency stimulation
gptkbp:involves gptkb:AMPA_receptor
gptkb:NMDA_receptor
protein synthesis
calcium influx
gptkbp:mechanismOfAction increase in synaptic strength
gptkbp:occurredIn gptkb:cerebral_cortex
hippocampus
amygdala
gptkbp:opposedBy long-term depression
gptkbp:relatedTo gptkb:Alzheimer's_disease
gptkb:synaptic_plasticity
epilepsy
memory
learning
cognitive function
gptkbp:studiedIn humans
rodents
gptkbp:bfsParent gptkb:brain-derived_neurotrophic_factor
gptkb:Hebbian_theory
gptkb:Hebbian_learning
gptkb:Post-Tetanic_Potentiation
gptkbp:bfsLayer 6