Statements (34)
Predicate | Object |
---|---|
gptkbp:instanceOf |
neurophysiological phenomenon
|
gptkbp:abbreviation |
gptkb:LTP
|
gptkbp:category |
neuroscience
synaptic transmission memory formation |
gptkbp:discoveredBy |
gptkb:Timothy_Bliss
gptkb:Terje_Lømo |
gptkbp:discoveredIn |
1973
|
gptkbp:duration |
hours to days or longer
|
gptkbp:firstObserved |
rabbit hippocampus
|
https://www.w3.org/2000/01/rdf-schema#label |
long-term potentiation
|
gptkbp:inducedBy |
high-frequency stimulation
|
gptkbp:involves |
gptkb:AMPA_receptor
gptkb:NMDA_receptor protein synthesis calcium influx |
gptkbp:mechanismOfAction |
increase in synaptic strength
|
gptkbp:occurredIn |
gptkb:cerebral_cortex
hippocampus amygdala |
gptkbp:opposedBy |
long-term depression
|
gptkbp:relatedTo |
gptkb:Alzheimer's_disease
gptkb:synaptic_plasticity epilepsy memory learning cognitive function |
gptkbp:studiedIn |
humans
rodents |
gptkbp:bfsParent |
gptkb:brain-derived_neurotrophic_factor
gptkb:Hebbian_theory gptkb:Hebbian_learning gptkb:Post-Tetanic_Potentiation |
gptkbp:bfsLayer |
6
|