Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
p190
p210 p230 |
| gptkbp:associatedWith |
leukemia
|
| gptkbp:cause |
uncontrolled cell proliferation
|
| gptkbp:chromosomalTranslocation |
t(9;22)(q34;q11)
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
BCR-ABL1 gene
|
| gptkbp:formedBy |
BCR gene
ABL gene |
| gptkbp:foundIn |
gptkb:Philadelphia_chromosome
gptkb:chronic_myeloid_leukemia |
| gptkbp:hasBiologicalActivity |
gptkb:receptor_tyrosine_kinase
|
| https://www.w3.org/2000/01/rdf-schema#label |
BCR-ABL protein
|
| gptkbp:locale |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
210 kDa
|
| gptkbp:target |
gptkb:bosutinib
gptkb:dasatinib gptkb:ponatinib gptkb:imatinib gptkb:nilotinib |
| gptkbp:bfsParent |
gptkb:BCR-ABL_fusion_gene
gptkb:Glivec |
| gptkbp:bfsLayer |
7
|