|
gptkbp:instanceOf
|
gptkb:leukemia
gptkb:disease
|
|
gptkbp:affects
|
gptkb:B_lymphocytes
adults
blood
bone marrow
|
|
gptkbp:canHaveGeneticAbnormality
|
gptkb:t(9;22)_Philadelphia_chromosome
hyperdiploidy
hypodiploidy
t(12;21)
|
|
gptkbp:cause
|
gptkb:anemia
thrombocytopenia
leukopenia
leukocytosis
|
|
gptkbp:commonIn
|
children
|
|
gptkbp:diagnosedBy
|
bone marrow biopsy
blood tests
immunophenotyping
flow cytometry
|
|
gptkbp:firstDescribed
|
20th century
|
|
gptkbp:ICD-10_code
|
gptkb:C91.0
|
|
gptkbp:marking
|
gptkb:CD22
gptkb:CD10
gptkb:TdT
gptkb:CD19
gptkb:PAX5
|
|
gptkbp:mayInclude
|
central nervous system
liver
lymph nodes
spleen
|
|
gptkbp:MeSH_ID
|
D015452
|
|
gptkbp:prognosis
|
generally good in children
worse in adults
|
|
gptkbp:relapseRisk
|
higher in adults
lower in children
|
|
gptkbp:subspecies
|
gptkb:leukemia
|
|
gptkbp:symptom
|
fever
bleeding
fatigue
recurrent infections
bone pain
easy bruising
|
|
gptkbp:treatment
|
gptkb:gene_therapy
gptkb:immunotherapy
chemotherapy
corticosteroids
stem cell transplant
|
|
gptkbp:bfsParent
|
gptkb:acute_lymphoblastic_leukemia_(ALL)
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
B-cell ALL
|