Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:disease
leukemia |
gptkbp:affects |
gptkb:B_lymphocytes
adults blood bone marrow |
gptkbp:canHaveGeneticAbnormality |
gptkb:t(9;22)_Philadelphia_chromosome
hyperdiploidy hypodiploidy t(12;21) |
gptkbp:cause |
gptkb:anemia
thrombocytopenia leukopenia leukocytosis |
gptkbp:commonIn |
children
|
gptkbp:diagnosedBy |
bone marrow biopsy
blood tests immunophenotyping flow cytometry |
gptkbp:firstDescribed |
20th century
|
https://www.w3.org/2000/01/rdf-schema#label |
B-cell ALL
|
gptkbp:ICD-10_code |
gptkb:C91.0
|
gptkbp:marking |
gptkb:CD22
gptkb:CD10 gptkb:TdT gptkb:CD19 gptkb:PAX5 |
gptkbp:mayInclude |
central nervous system
liver lymph nodes spleen |
gptkbp:MeSH_ID |
D015452
|
gptkbp:prognosis |
generally good in children
worse in adults |
gptkbp:relapseRisk |
higher in adults
lower in children |
gptkbp:subspecies |
leukemia
|
gptkbp:symptom |
fever
bleeding fatigue recurrent infections bone pain easy bruising |
gptkbp:treatment |
chemotherapy
immunotherapy gene therapy corticosteroids stem cell transplant |
gptkbp:bfsParent |
gptkb:leukemia
|
gptkbp:bfsLayer |
5
|