|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:AGO_protein
gptkb:PIWI_protein
|
|
gptkbp:binds
|
microRNAs
siRNAs
small RNAs
|
|
gptkbp:contains
|
PAZ domain
PIWI domain
|
|
gptkbp:encodedBy
|
AGO genes
|
|
gptkbp:firstDescribed
|
2001
|
|
gptkbp:foundIn
|
prokaryotes
eukaryotes
|
|
gptkbp:function
|
gptkb:RNA_interference
gene silencing
|
|
gptkbp:hasBiologicalActivity
|
endoribonuclease
|
|
gptkbp:hasMember
|
gptkb:AGO1
gptkb:AGO2
gptkb:AGO3
gptkb:PIWI_proteins
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Argonaute
|
|
gptkbp:interactsWith
|
gptkb:RNA-induced_silencing_complex_(RISC)
gptkb:Dicer
|
|
gptkbp:involvedIn
|
defense against viruses
post-transcriptional gene regulation
transposon silencing
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:mechanismOfAction
|
translational repression
cleavage of target RNA
deadenylation of mRNA
|
|
gptkbp:namedAfter
|
gptkb:Argonaute_octopus
|
|
gptkbp:orthologIn
|
eukaryotic Argonautes
prokaryotic Argonautes
|
|
gptkbp:relatedTo
|
RNA silencing
epigenetic regulation
genome defense
|
|
gptkbp:requires
|
microRNA pathway
siRNA pathway
|
|
gptkbp:structure
|
bilobal
|
|
gptkbp:studiedIn
|
gptkb:Homo_sapiens
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
gptkb:Arabidopsis_thaliana
|
|
gptkbp:bfsParent
|
gptkb:French_fleet_at_Trafalgar
|
|
gptkbp:bfsLayer
|
7
|