RNA-induced silencing complex (RISC)
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
RNA silencing complex
RNAi effector complex |
| gptkbp:binds |
gptkb:guide_RNA
target mRNA |
| gptkbp:component |
gptkb:microRNA_(miRNA)
gptkb:small_interfering_RNA_(siRNA) gptkb:Argonaute_protein |
| gptkbp:discoveredIn |
1999
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
gptkb:RNA_interference
gene silencing |
| https://www.w3.org/2000/01/rdf-schema#label |
RNA-induced silencing complex (RISC)
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:mechanismOfAction |
mRNA degradation
translational repression mRNA cleavage |
| gptkbp:regulates |
gene expression
|
| gptkbp:relatedTo |
RNA silencing
post-transcriptional gene silencing |
| gptkbp:bfsParent |
gptkb:small_interfering_RNA_(siRNA)
|
| gptkbp:bfsLayer |
7
|