Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
| gptkbp:binds |
gptkb:heparan_sulfate_proteoglycans
gptkb:LDL_receptor |
| gptkbp:discoveredIn |
1973
|
| gptkbp:encodedBy |
gptkb:APOE_gene
|
| gptkbp:expressedIn |
brain
liver macrophages |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:fullName |
gptkb:Apolipoprotein_E
|
| gptkbp:function |
cholesterol metabolism
lipid transport |
| gptkbp:hasIsoform |
gptkb:ApoE2
gptkb:ApoE3 gptkb:ApoE4 |
| gptkbp:hasPolymorphism |
gptkb:E4
gptkb:E2 gptkb:E3 |
| https://www.w3.org/2000/01/rdf-schema#label |
Apo-E
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19
|
| gptkbp:molecularWeight |
34 kDa
|
| gptkbp:OMIM |
107741
|
| gptkbp:riskFactor |
gptkb:late-onset_Alzheimer's_disease
gptkb:hyperlipoproteinemia_type_III atherosclerosis |
| gptkbp:role |
gptkb:cardiovascular_disease
lipoprotein metabolism |
| gptkbp:structure |
299 amino acids
|
| gptkbp:UniProtID |
P02649
|
| gptkbp:bfsParent |
gptkb:apolipoprotein_E
|
| gptkbp:bfsLayer |
6
|