Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hormone
estrogen |
| gptkbp:alsoKnownAs |
gptkb:estradiol
|
| gptkbp:CASNumber |
50-28-2
|
| gptkbp:chemicalFormula |
C18H24O2
|
| gptkbp:excretion |
urine
bile |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
bone health
maintenance of pregnancy regulation of cholesterol levels regulation of menstrual cycle development of female secondary sexual characteristics |
| gptkbp:halfLife |
13-20 hours
|
| https://www.w3.org/2000/01/rdf-schema#label |
E2
|
| gptkbp:IUPACName |
estra-1,3,5(10)-triene-3,17β-diol
|
| gptkbp:KEGGID |
D00103
|
| gptkbp:meltingPoint |
173-179 °C
|
| gptkbp:MeSH_ID |
D004967
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
272.38 g/mol
|
| gptkbp:predecessor |
estradiol sulfate
estriol estrone estrone sulfate |
| gptkbp:producedBy |
gptkb:placenta
adrenal glands ovaries testes |
| gptkbp:PubChem_CID |
gptkb:CHEMBL691
gptkb:DB00783 5757 |
| gptkbp:recipient |
estrogen receptor alpha
estrogen receptor beta |
| gptkbp:routeOfAdministration |
injection
oral transdermal vaginal |
| gptkbp:sideEffect |
nausea
headache breast tenderness increased risk of blood clots increased risk of breast cancer increased risk of stroke |
| gptkbp:UNII |
4TI98Z838E
|
| gptkbp:usedAs |
gptkb:drug
|
| gptkbp:usedFor |
gptkb:cancer
prostate cancer hormone therapy hypoestrogenism menopausal symptoms |
| gptkbp:bfsParent |
gptkb:Let's_Encrypt
|
| gptkbp:bfsLayer |
4
|