Apolipoprotein E

GPTKB entity

Statements (66)
Predicate Object
gptkbp:instance_of gptkb:protein
gptkbp:associated_with gptkb:psychologist
gptkbp:combatants LDL receptors
gptkbp:constructed_in gptkb:Person
gptkbp:function Lipid transport
gptkbp:has_role Synaptic repair
gptkbp:has_variants gptkb:APOE_ε2
gptkb:APOE_ε3
gptkb:APOE_ε4
https://www.w3.org/2000/01/rdf-schema#label Apolipoprotein E
gptkbp:influences Atherosclerosis risk
gptkbp:is_a Lipoprotein
gptkbp:is_associated_with gptkb:psychologist
Multiple sclerosis
Cardiovascular disease
Obesity
Huntington's disease
Chronic kidney disease
Neurodegenerative diseases
Age-related macular degeneration
Cognitive impairment
Cerebral amyloid angiopathy
gptkbp:is_found_in Cerebrospinal fluid
gptkbp:is_involved_in Cell signaling
Inflammation
Synaptic plasticity
Neuroinflammation
Endocytosis
Neurotransmitter release
Cholesterol homeostasis
Neuroprotection
Neurodegeneration
Cellular repair mechanisms
Vascular health
Neuronal survival
Lipid droplet formation
Synaptic function
Amyloid plaque formation
Cellular cholesterol efflux
Fatty acid transport
Lipid metabolism disorders
Neuronal repair
Neurotransmitter metabolism
gptkbp:is_linked_to gptkb:Traumatic_brain_injury
Neurodegenerative disorders
Cognitive decline
Metabolic syndrome
Sleep disorders
Chronic inflammation
Cognitive health
Age-related cognitive decline
Cognitive decline in aging
Cognitive resilience
Diabetes risk
gptkbp:is_part_of Lipid metabolism pathway
gptkbp:is_represented_in gptkb:skincare_product
gptkbp:measures Blood tests
gptkbp:produced_by Liver
gptkbp:promoter gptkb:APOE
gptkbp:regulates Estrogen
gptkbp:role Cholesterol metabolism
gptkbp:security_features Astrocytes
gptkbp:transportation Chylomicrons
gptkbp:type gptkb:poet
gptkbp:bfsParent gptkb:APOE_ε3
gptkbp:bfsLayer 8