Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affects |
cholesterol transport
|
| gptkbp:aminoAcidChange |
Cys112, Cys158
|
| gptkbp:associatedWith |
gptkb:type_III_hyperlipoproteinemia
|
| gptkbp:distinctFrom |
gptkb:ApoE3
gptkb:ApoE4 |
| gptkbp:encodedBy |
gptkb:APOE_gene
|
| gptkbp:foundIn |
humans
|
| gptkbp:fullName |
gptkb:Apolipoprotein_E2
|
| gptkbp:hasAlleleFrequency |
~8% in European populations
|
| gptkbp:hasAminoAcidAtPosition112 |
gptkb:Cysteine
|
| gptkbp:hasAminoAcidAtPosition158 |
gptkb:Cysteine
|
| gptkbp:hasIsoelectricPoint |
5.9
|
| gptkbp:hasSNP |
gptkb:rs7412
|
| https://www.w3.org/2000/01/rdf-schema#label |
ApoE2
|
| gptkbp:involvedIn |
lipid metabolism
|
| gptkbp:lessEfficientAt |
binding to LDL receptor
|
| gptkbp:memberOf |
gptkb:apolipoprotein_E_family
|
| gptkbp:molecularWeight |
34 kDa
|
| gptkbp:protectedBy |
gptkb:Alzheimer's_disease
|
| gptkbp:significance |
gptkb:dysbetalipoproteinemia
|
| gptkbp:bfsParent |
gptkb:apolipoprotein_E2
gptkb:Apo-E gptkb:ApoE |
| gptkbp:bfsLayer |
7
|