Statements (71)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:AD_Genetics
|
| gptkbp:associated_with |
gptkb:hospital
gptkb:psychologist |
| gptkbp:clinical_trial |
risk factor for Alzheimer's disease
|
| gptkbp:code |
gptkb:apolipoprotein_E
|
| gptkbp:discovered_by |
gptkb:John_C._Fridovich
|
| gptkbp:has_method |
transporting cholesterol
|
| gptkbp:has_role |
neuronal repair
|
| gptkbp:has_variants |
gptkb:APOE_ε2
gptkb:APOE_ε3 gptkb:APOE_ε4 |
| https://www.w3.org/2000/01/rdf-schema#label |
APOE gene
|
| gptkbp:influences |
amyloid plaque formation
|
| gptkbp:is_associated_with |
gptkb:psychologist
schizophrenia anxiety disorders bipolar disorder traumatic brain injury chronic kidney disease type 2 diabetes cognitive impairment vascular dementia |
| gptkbp:is_involved_in |
cell signaling
immune response lipid metabolism neurotransmitter release neuroinflammation oxidative stress response synaptic plasticity neuroprotection cellular signaling pathways neurodegeneration synaptic function neuronal survival cellular repair mechanisms neurotransmitter metabolism lipid droplet formation cellular cholesterol efflux cholesterol homeostasis |
| gptkbp:is_linked_to |
gptkb:psychologist
cognitive decline chronic diseases metabolic syndrome obesity sleep disorders atherosclerosis chronic inflammation mood disorders cognitive resilience |
| gptkbp:is_part_of |
lipid transport pathway
lipoprotein particles |
| gptkbp:is_recognized_by |
gptkb:1980s
|
| gptkbp:is_represented_in |
gptkb:microprocessor
gptkb:skincare_product liver microglia astrocytes |
| gptkbp:is_studied_in |
clinical trials
genetic testing personalized medicine population genetics therapeutic interventions genetic epidemiology therapeutic targets neurogenetics biomarker development |
| gptkbp:located_in |
chromosome 19
|
| gptkbp:regulates |
transcription factors
|
| gptkbp:targets |
gptkb:physicist
|