|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD143
gptkb:DCP1
gptkb:kininase_II
gptkb:peptidyl-dipeptidase_A
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cardiovascular_disease
hypertension
|
|
gptkbp:biologicalProcess
|
gptkb:renin-angiotensin_system
regulation of blood pressure
peptidyl-dipeptidase activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:encodes
|
gptkb:angiotensin-converting_enzyme
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000159640
1636
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
endothelial cells
|
|
gptkbp:fullName
|
gptkb:angiotensin_I_converting_enzyme
|
|
gptkbp:function
|
inactivates bradykinin
converts angiotensin I to angiotensin II
|
|
gptkbp:hasPolymorphism
|
I/D polymorphism
|
|
gptkbp:HGNC_ID
|
2707
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ACE1
|
|
gptkbp:involvedIn
|
blood pressure regulation
electrolyte homeostasis
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_17
|
|
gptkbp:OMIM
|
106180
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Ace
|
|
gptkbp:product
|
gptkb:angiotensin-converting_enzyme
|
|
gptkbp:target
|
ACE inhibitors
|
|
gptkbp:UniProtID
|
P12821
|
|
gptkbp:bfsParent
|
gptkb:ACE2_receptor
|
|
gptkbp:bfsLayer
|
7
|