Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
gptkb:ADORA3
adenosine receptor A3 |
| gptkbp:binds |
gptkb:adenosine
|
| gptkbp:couplingType |
gptkb:Gi_protein
Go protein |
| gptkbp:encodedBy |
ADORA3 gene
|
| gptkbp:enemyOf |
Cl-IB-MECA
IB-MECA MRS 1191 MRS 1220 MRS 1523 |
| gptkbp:expressedIn |
gptkb:cancer
gptkb:testis brain heart liver immune cells |
| gptkbp:family |
adenosine receptor family
|
| gptkbp:foundIn |
gptkb:human
gptkb:mouse right |
| gptkbp:function |
involved in inflammation
inhibits adenylyl cyclase modulates immune response involved in cardioprotection |
| https://www.w3.org/2000/01/rdf-schema#label |
A3 adenosine receptor
|
| gptkbp:locatedOnChromosome |
chromosome 1 (human)
|
| gptkbp:modulatedBy |
gptkb:MAPK_pathway
gptkb:PI3K_pathway apoptosis cell proliferation calcium signaling cytokine release |
| gptkbp:relatedTo |
gptkb:cancer
asthma inflammatory diseases ischemia neuroprotection |
| gptkbp:structureType |
seven transmembrane domain protein
|
| gptkbp:subfamily |
purinergic receptor
|
| gptkbp:targetOfDrug |
anticancer drugs
anti-inflammatory drugs cardioprotective drugs neuroprotective drugs |
| gptkbp:UniProtID |
P33765
|
| gptkbp:bfsParent |
gptkb:adenosine_receptor
|
| gptkbp:bfsLayer |
6
|