|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:A3
A3AR
adenosine receptor A3
|
|
gptkbp:associatedWith
|
inflammatory response
neuroprotection
cardioprotection
|
|
gptkbp:discoveredBy
|
1993
|
|
gptkbp:encodes
|
Adenosine A3 receptor
|
|
gptkbp:enemyOf
|
Cl-IB-MECA
IB-MECA
MRS1191
MRS1220
MRS1523
|
|
gptkbp:Entrez_Gene_ID
|
140
ENSG00000157224
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:testis
brain
heart
liver
|
|
gptkbp:function
|
G protein-coupled adenosine receptor activity
adenosine receptor activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:262
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ADORA3
|
|
gptkbp:ligand
|
gptkb:adenosine
|
|
gptkbp:locatedOnChromosome
|
1p13.2
chromosome 1
|
|
gptkbp:modulatedBy
|
apoptosis
cell proliferation
inflammation
immune response
|
|
gptkbp:OMIM
|
600045
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:recipient
|
purinergic receptor
|
|
gptkbp:relatedTo
|
gptkb:ADORA1
gptkb:ADORA2A
gptkb:ADORA2B
|
|
gptkbp:targetOfDrug
|
gptkb:cancer
cardiovascular diseases
inflammatory diseases
neurological disorders
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:type
|
inhibits adenylyl cyclase via Gi protein
|
|
gptkbp:UniProtID
|
P33765
|
|
gptkbp:bfsParent
|
gptkb:adenosine_receptor
|
|
gptkbp:bfsLayer
|
6
|