vinculin

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeSplicing metavinculin
gptkbp:discoveredBy Benjamin Geiger
gptkbp:discoveredIn 1979
gptkbp:encodedBy VCL gene
gptkbp:foundIn cell-cell junctions
focal adhesions
gptkbp:function cell adhesion
linking integrin adhesion molecules to the actin cytoskeleton
https://www.w3.org/2000/01/rdf-schema#label vinculin
gptkbp:interactsWith gptkb:actin
gptkb:alpha-actinin
gptkb:paxillin
gptkb:talin
gptkbp:locale gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:locatedOnChromosome chromosome 10q22.1-q23
gptkbp:molecularWeight 116 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:role cell migration
cell signaling
regulation of cell motility
regulation of cell shape
mechanotransduction
gptkbp:structure composed of head, neck, and tail domains
gptkbp:UniProtID P18206
gptkbp:bfsParent gptkb:Focal_adhesion_kinase
gptkb:paxillin
gptkb:talin
gptkbp:bfsLayer 7